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Genetic variants in LEKR1 and GALNT10 modulate sex-difference in carotid intima-media thickness: a genome-wide interaction study.

Dong C, Della-Morte D, Beecham A et al.

25898001 PubMed ID
GWAS Study Type
1341 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

DC
Dong C
DD
Della-Morte D
BA
Beecham A
WL
Wang L
CD
Cabral D
BS
Blanton SH
SR
Sacco RL
RT
Rundek T
Chapter II

Abstract

Summary of the research findings

There is an established sex-difference in carotid artery intima-media thickness (cIMT), a recognized marker of subclinical atherosclerosis. However, the genetic underpinnings of sex-differences in gene-IMT associations are largely unknown.

931 Hispanic individuals

Chapter III

Study Statistics

Key metrics and study information

1341
Total Participants
GWAS
Study Type
Yes
Replicated
153 European ancestry individuals, 257 Black individuals
Replication Participants
European, Hispanic or Latin American, African American or Afro-Caribbean
Ancestry
U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

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