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GWAS Study

Polymorphism at 19q13.41 Predicts Breast Cancer Survival Specifically after Endocrine Therapy.

Khan S, Fagerholm R, Rafiq S et al.

25964295 PubMed ID
GWAS Study Type
4011 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

KS
Khan S
FR
Fagerholm R
RS
Rafiq S
TW
Tapper W
AK
Aittomäki K
LJ
Liu J
BC
Blomqvist C
ED
Eccles D
NH
Nevanlinna H
Chapter II

Abstract

Summary of the research findings

Purpose: Although most patients with estrogen receptor (ER)-positive breast cancer benefit from endocrine therapies, a significant proportion do not. Our aim was to identify inherited genetic variations that might predict survival among patients receiving adjuvant endocrine therapies.

639 European ancestry cases

Chapter III

Study Statistics

Key metrics and study information

4011
Total Participants
GWAS
Study Type
Yes
Replicated
3,372 European ancestry cases
Replication Participants
European
Ancestry
Finland, U.K., Germany
Recruitment Country
Chapter IV

AI-Generated Summary

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