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GWAS Study

Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study.

Li Z, Xia Y, Feng LN et al.

27470079 PubMed ID
GWAS Study Type
7482 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

LZ
Li Z
XY
Xia Y
FL
Feng LN
CJ
Chen JR
LH
Li HM
CJ
Cui J
CQ
Cai QQ
SK
Sim KS
NM
Nairismägi ML
LY
Laurensia Y
MW
Meah WY
LW
Liu WS
GY
Guo YM
CL
Chen LZ
FQ
Feng QS
PC
Pang CP
CL
Chen LJ
CS
Chew SH
ER
Ebstein RP
FJ
Foo JN
LJ
Liu J
HJ
Ha J
KL
Khoo LP
CS
Chin ST
ZY
Zeng YX
AT
Aung T
CB
Chowbay B
DC
Diong CP
ZF
Zhang F
LY
Liu YH
TT
Tang T
TM
Tao M
QR
Quek R
MF
Mohamad F
TS
Tan SY
TB
Teh BT
NS
Ng SB
CW
Chng WJ
OC
Ong CK
OY
Okada Y
RS
Raychaudhuri S
LS
Lim ST
TW
Tan W
PR
Peng RJ
KC
Khor CC
BJ
Bei JX
Chapter II

Abstract

Summary of the research findings

Extranodal natural killer T-cell lymphoma (NKTCL), nasal type, is a rare and aggressive malignancy that occurs predominantly in Asian and Latin American populations. Although Epstein-Barr virus infection is a known risk factor, other risk factors and the pathogenesis of NKTCL are not well understood. We aimed to identify common genetic variants affecting individual risk of NKTCL.

189 East Asian ancestry cases, 957 East Asian ancestry controls

Chapter III

Study Statistics

Key metrics and study information

7482
Total Participants
GWAS
Study Type
Yes
Replicated
514 East Asian ancestry cases, 5,822 East Asian ancestry controls
Replication Participants
East Asian
Ancestry
China, Hong Kong SAR, Singapore
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.