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GWAS Study

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function.

Wild PS, Felix JF, Schillert A et al.

28394258 PubMed ID
GWAS Study Type
36639 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

WP
Wild PS
FJ
Felix JF
SA
Schillert A
TA
Teumer A
CM
Chen MH
LM
Leening MJG
VU
Völker U
GV
Großmann V
BJ
Brody JA
IM
Irvin MR
SS
Shah SJ
PS
Pramana S
LW
Lieb W
SR
Schmidt R
SA
Stanton AV
MD
Malzahn D
SA
Smith AV
SJ
Sundström J
MC
Minelli C
RD
Ruggiero D
LL
Lyytikäinen LP
TD
Tiller D
SJ
Smith JG
MC
Monnereau C
DT
Di Tullio MR
MS
Musani SK
MA
Morrison AC
PT
Pers TH
MM
Morley M
KM
Kleber ME
AJ
Aragam J
BE
Benjamin EJ
BJ
Bis JC
BE
Bisping E
BU
Broeckel U
CS
Cheng S
DJ
Deckers JW
DG
Del Greco M F
EF
Edelmann F
FM
Fornage M
FL
Franke L
FN
Friedrich N
HT
Harris TB
HE
Hofer E
HA
Hofman A
HJ
Huang J
HA
Hughes AD
KM
Kähönen M
IK
Investigators K
KJ
Kruppa J
LK
Lackner KJ
LL
Lannfelt L
LR
Laskowski R
LL
Launer LJ
LM
Leosdottir M
LH
Lin H
LC
Lindgren CM
LC
Loley C
MC
MacRae CA
MD
Mascalzoni D
MJ
Mayet J
MD
Medenwald D
MA
Morris AP
MC
Müller C
MM
Müller-Nurasyid M
NS
Nappo S
NP
Nilsson PM
NS
Nuding S
NT
Nutile T
PA
Peters A
PA
Pfeufer A
PD
Pietzner D
PP
Pramstaller PP
RO
Raitakari OT
RK
Rice KM
RF
Rivadeneira F
RJ
Rotter JI
RS
Ruohonen ST
SR
Sacco RL
ST
Samdarshi TE
SH
Schmidt H
SA
Sharp ASP
SD
Shields DC
SR
Sorice R
SN
Sotoodehnia N
SB
Stricker BH
SP
Surendran P
TS
Thom S
TA
Töglhofer AM
UA
Uitterlinden AG
WR
Wachter R
VH
Völzke H
ZA
Ziegler A
MT
Münzel T
MW
März W
CT
Cappola TP
HJ
Hirschhorn JN
MG
Mitchell GF
SN
Smith NL
FE
Fox ER
DN
Dueker ND
JV
Jaddoe VWV
MO
Melander O
RM
Russ M
LT
Lehtimäki T
CM
Ciullo M
HA
Hicks AA
LL
Lind L
GV
Gudnason V
PB
Pieske B
BA
Barron AJ
ZR
Zweiker R
SH
Schunkert H
IE
Ingelsson E
LK
Liu K
AD
Arnett DK
PB
Psaty BM
BS
Blankenberg S
LM
Larson MG
FS
Felix SB
FO
Franco OH
ZT
Zeller T
VR
Vasan RS
DM
Dörr M
Chapter II

Abstract

Summary of the research findings

Understanding the genetic architecture of cardiac structure and function may help to prevent and treat heart disease. This investigation sought to identify common genetic variations associated with inter-individual variability in cardiac structure and function.

21,852 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

36639
Total Participants
GWAS
Study Type
Yes
Replicated
14,787 European ancestry individuals
Replication Participants
European
Ancestry
Germany, Netherlands, Finland, Sweden, Italy, U.S., Iceland, Republic of Ireland, U.K., Austria
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

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