Genetic variation in the gene LRP2 increases relapse risk in multiple sclerosis.
Zhou Y, Graves JS, Simpson S et al.
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Abstract
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Due to the lack of prospective studies with longitudinal data on relapse, past genetic studies have not attempted to identify genetic factors that predict relapse risk (the primary endpoint of many pivotal clinical trials testing the efficacy of multiple sclerosis (MS) disease-modifying drugs) at a genome-wide scale.
268 cases
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