Menu
Currency
GWAS Study

Female-specific Association Between Variants on Chromosome 9 and Self-reported Diagnosis of Irritable Bowel Syndrome.

Bonfiglio F, Zheng T, Garcia-Etxebarria K et al.

29626450 PubMed ID
GWAS Study Type
346075 Participants
71 Views
Scroll to explore
Chapter I

Publication Details

Comprehensive information about this research publication

Authors

BF
Bonfiglio F
ZT
Zheng T
GK
Garcia-Etxebarria K
HF
Hadizadeh F
BL
Bujanda L
BF
Bresso F
AL
Agreus L
AA
Andreasson A
DA
Dlugosz A
LG
Lindberg G
SP
Schmidt PT
KP
Karling P
OB
Ohlsson B
SM
Simren M
WS
Walter S
NG
Nardone G
CR
Cuomo R
UP
Usai-Satta P
GF
Galeazzi F
NM
Neri M
PP
Portincasa P
BM
Bellini M
BG
Barbara G
LA
Latiano A
HM
Hübenthal M
TV
Thijs V
NM
Netea MG
JD
Jonkers D
CL
Chang L
ME
Mayer EA
WM
Wouters MM
BG
Boeckxstaens G
CM
Camilleri M
FA
Franke A
ZA
Zhernakova A
DM
D'Amato M
Chapter II

Abstract

Summary of the research findings

Background & aims: Genetic factors are believed to affect risk for irritable bowel syndrome (IBS), but there have been no sufficiently powered and adequately sized studies. To identify DNA variants associated with IBS risk, we performed a genome-wide association study (GWAS) of the large UK Biobank population-based cohort, which includes genotype and health data from 500,000 participants.

7,130 British ancestry women cases, 2,446 British ancestry men cases, 178,076 British ancestry women controls, 158,423 British ancestry men controls

Chapter III

Study Statistics

Key metrics and study information

346075
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.K.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

AI Summary In Progress

Our AI-generated summary of this publication is being prepared. Please check back soon.