Menu
Currency
GWAS Study

Genome-wide association study meta-analysis identifies five new loci for systemic lupus erythematosus.

Julià A, López-Longo FJ, Pérez Venegas JJ et al.

29848360 PubMed ID
GWAS Study Type
16966 Participants
184 Views
Scroll to explore
Chapter I

Publication Details

Comprehensive information about this research publication

Authors

JA
Julià A
LF
López-Longo FJ
PV
Pérez Venegas JJ
BS
Bonàs-Guarch S
Olivé À
AJ
Andreu JL
AM
Aguirre-Zamorano MÁ
VP
Vela P
NJ
Nolla JM
DL
de la Fuente JLM
ZA
Zea A
PJ
Pego-Reigosa JM
FM
Freire M
DE
Díez E
RE
Rodríguez-Almaraz E
CP
Carreira P
BR
Blanco R
TV
Taboada VM
LM
López-Lasanta M
CM
Corbeto ML
MJ
Mercader JM
TD
Torrents D
AD
Absher D
MS
Marsal S
FA
Fernández-Nebro A
Chapter II

Abstract

Summary of the research findings

Systemic lupus erythematosus (SLE) is a common systemic autoimmune disease with a complex genetic inheritance. Genome-wide association studies (GWAS) have significantly increased the number of significant loci associated with SLE risk. To date, however, established loci account for less than 30% of the disease heritability and additional risk variants have yet to be identified. Here we performed a GWAS followed by a meta-analysis to identify new genome-wide significant loci for SLE.

4,943 European ancestry cases, 8,483 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

16966
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Spain
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

AI Summary In Progress

Our AI-generated summary of this publication is being prepared. Please check back soon.