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GWAS Study

Bivariate Genome-Wide Association Scan Identifies 6 Novel Loci Associated With Lipid Levels and Coronary Artery Disease.

Siewert KM, Voight BF

30525989 PubMed ID
GWAS Study Type
735838 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SK
Siewert KM
VB
Voight BF
Chapter II

Abstract

Summary of the research findings

Plasma lipid levels are heritable and genetically associated with risk of coronary artery disease (CAD). However, genome-wide association studies (GWAS) routinely analyze these traits independent of one another. Joint GWAS for two related phenotypes can lead to a higher powered analysis to detect variants contributing to both traits.

122,733 coronary artery disease cases, 424,528 coronary artery disease controls, 188,577 individuals

Chapter III

Study Statistics

Key metrics and study information

735838
Total Participants
GWAS
Study Type
No
Replicated
NR, European
Ancestry
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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