Menu
Currency
GWAS Study

Meta-analysis of Immunochip data of four autoimmune diseases reveals novel single-disease and cross-phenotype associations.

Márquez A, Kerick M, Zhernakova A et al.

30572963 PubMed ID
GWAS Study Type
59467 Participants
79 Views
Scroll to explore
Chapter I

Publication Details

Comprehensive information about this research publication

Authors

MA
Márquez A
KM
Kerick M
ZA
Zhernakova A
GJ
Gutierrez-Achury J
CW
Chen WM
OS
Onengut-Gumuscu S
GI
González-Álvaro I
RL
Rodriguez-Rodriguez L
RR
Rios-Fernández R
GM
González-Gay MA
MM
Mayes MD
RS
Raychaudhuri S
RS
Rich SS
WC
Wijmenga C
MJ
Martín J
Chapter II

Abstract

Summary of the research findings

In recent years, research has consistently proven the occurrence of genetic overlap across autoimmune diseases, which supports the existence of common pathogenic mechanisms in autoimmunity. The objective of this study was to further investigate this shared genetic component.

11,489 European ancestry cases with celiac disease, 15,523 European ancestry cases with rheumatoid arthritis, 3,477 European ancestry cases with systemic sclerosis, 6,670 European ancestry cases with type 1 diabetes, 22,308 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

59467
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Italy, Netherlands, Spain, Sweden, U.K., U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

AI Summary In Progress

Our AI-generated summary of this publication is being prepared. Please check back soon.