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GWAS Study

Genome-wide association study of type 2 diabetes in Africa.

Chen J, Sun M, Adeyemo A et al.

31049640 PubMed ID
GWAS Study Type
4347 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

CJ
Chen J
SM
Sun M
AA
Adeyemo A
PF
Pirie F
CT
Carstensen T
PC
Pomilla C
DA
Doumatey AP
CG
Chen G
YE
Young EH
SM
Sandhu M
MA
Morris AP
BI
Barroso I
MM
McCarthy MI
MA
Mahajan A
WE
Wheeler E
RC
Rotimi CN
MA
Motala AA
Chapter II

Abstract

Summary of the research findings

Aims/hypothesis: Genome-wide association studies (GWAS) for type 2 diabetes have uncovered >400 risk loci, primarily in populations of European and Asian ancestry. Here, we aimed to discover additional type 2 diabetes risk loci (including African-specific variants) and fine-map association signals by performing genetic analysis in African populations.

2,633 African ancestry cases, 1,714 African ancestry controls

Chapter III

Study Statistics

Key metrics and study information

4347
Total Participants
GWAS
Study Type
No
Replicated
Sub-Saharan African
Ancestry
Kenya, South Africa, Ghana, Nigeria
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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