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GWAS Study

Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout.

Kawamura Y, Nakaoka H, Nakayama A et al.

31289104 PubMed ID
GWAS Study Type
6009 Participants
65 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

KY
Kawamura Y
NH
Nakaoka H
NA
Nakayama A
OY
Okada Y
YK
Yamamoto K
HT
Higashino T
SM
Sakiyama M
ST
Shimizu T
OH
Ooyama H
OK
Ooyama K
NM
Nagase M
HY
Hidaka Y
SY
Shirahama Y
HK
Hosomichi K
NY
Nishida Y
SI
Shimoshikiryo I
HA
Hishida A
KS
Katsuura-Kamano S
SS
Shimizu S
KM
Kawaguchi M
UH
Uemura H
IR
Ibusuki R
HM
Hara M
NM
Naito M
TM
Takao M
NM
Nakajima M
IS
Iwasawa S
NH
Nakashima H
OK
Ohnaka K
NT
Nakamura T
SB
Stiburkova B
MT
Merriman TR
NM
Nakatochi M
IS
Ichihara S
YM
Yokota M
TT
Takada T
ST
Saitoh T
KY
Kamatani Y
TA
Takahashi A
AK
Arisawa K
TT
Takezaki T
TK
Tanaka K
WK
Wakai K
KM
Kubo M
HT
Hosoya T
IK
Ichida K
II
Inoue I
SN
Shinomiya N
MH
Matsuo H
Chapter II

Abstract

Summary of the research findings

Objective: The first ever genome-wide association study (GWAS) of clinically defined gout cases and asymptomatic hyperuricaemia (AHUA) controls was performed to identify novel gout loci that aggravate AHUA into gout.

945 Japanese ancestry cases, 1,003 Japanese ancestry controls

Chapter III

Study Statistics

Key metrics and study information

6009
Total Participants
GWAS
Study Type
Yes
Replicated
1,915 Japanese ancestry cases, 2,146 Japanese ancestry controls
Replication Participants
East Asian
Ancestry
Japan
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

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