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GWAS Study

Clinical and Genome-Wide Analysis of Serum Platinum Levels after Cisplatin-Based Chemotherapy.

Trendowski MR, El-Charif O, Ratain MJ et al.

31296530 PubMed ID
GWAS Study Type
1010 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

TM
Trendowski MR
EO
El-Charif O
RM
Ratain MJ
MP
Monahan P
MZ
Mu Z
WH
Wheeler HE
DP
Dinh PC
FD
Feldman DR
AS
Ardeshir-Rouhani-Fard S
HR
Hamilton RJ
VD
Vaughn DJ
FC
Fung C
KC
Kollmannsberger C
MT
Mushiroda T
KM
Kubo M
HR
Hannigan R
SF
Strathmann F
EL
Einhorn LH
FS
Fossa SD
TL
Travis LB
DM
Dolan ME
Chapter II

Abstract

Summary of the research findings

Purpose: Serum platinum is measurable for years after completion of cisplatin-based chemotherapy (CBC). We report the largest investigation of serum platinum levels to date of 1,010 testicular cancer survivors (TCS) assessed 1-35 years after CBC and evaluate genetic contributions to these levels.

866 European ancestry individuals, 17 non-European ancestry individuals, 127 individuals

Chapter III

Study Statistics

Key metrics and study information

1010
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Canada, U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

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