Menu
GWAS Study

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies.

Nalls MA, Blauwendraat C, Vallerga CL et al.

31701892 PubMed ID
GWAS Study Type
1474097 Participants
Scroll to explore
Chapter I

Publication Details

Comprehensive information about this research publication

Authors

NM
Nalls MA
BC
Blauwendraat C
VC
Vallerga CL
HK
Heilbron K
BS
Bandres-Ciga S
CD
Chang D
TM
Tan M
KD
Kia DA
NA
Noyce AJ
XA
Xue A
BJ
Bras J
YE
Young E
VC
von Coelln R
SJ
Simón-Sánchez J
SC
Schulte C
SM
Sharma M
KL
Krohn L
PL
Pihlstrøm L
SA
Siitonen A
IH
Iwaki H
LH
Leonard H
FF
Faghri F
GJ
Gibbs JR
HD
Hernandez DG
SS
Scholz SW
BJ
Botia JA
MM
Martinez M
CJ
Corvol JC
LS
Lesage S
JJ
Jankovic J
SL
Shulman LM
SM
Sutherland M
TP
Tienari P
MK
Majamaa K
TM
Toft M
AO
Andreassen OA
BT
Bangale T
BA
Brice A
YJ
Yang J
GZ
Gan-Or Z
GT
Gasser T
HP
Heutink P
SJ
Shulman JM
WN
Wood NW
HD
Hinds DA
HJ
Hardy JA
MH
Morris HR
GJ
Gratten J
VP
Visscher PM
GR
Graham RR
SA
Singleton AB
Chapter II

Abstract

Summary of the research findings

Genome-wide association studies (GWAS) in Parkinson's disease have increased the scope of biological knowledge about the disease over the past decade. We aimed to use the largest aggregate of GWAS data to identify novel risk loci and gain further insight into the causes of Parkinson's disease.

15,056 European ancestry cases, 18,618 European ancestry proxy cases, 449,056 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

1474097
Total Participants
GWAS
Study Type
Yes
Replicated
22,632 European ancestry cases, 968,735 European ancestry controls
Replication Participants
European
Ancestry
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.