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GWAS Study

Association of FADS1/2 Locus Variants and Polyunsaturated Fatty Acids With Aortic Stenosis.

Chen HY, Cairns BJ, Small AM et al.

32186652 PubMed ID
GWAS Study Type
312118 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

CH
Chen HY
CB
Cairns BJ
SA
Small AM
BH
Burr HA
AA
Ambikkumar A
MA
Martinsson A
TS
Thériault S
MH
Munter HM
SB
Steffen B
ZR
Zhang R
LR
Levinson RT
SC
Shaffer CM
RJ
Rong J
SE
Sonestedt E
DL
Dufresne L
LJ
Ljungberg J
NU
Näslund U
JB
Johansson B
RD
Ranatunga DK
WR
Whitmer RA
BM
Budoff MJ
NA
Nguyen A
VR
Vasan RS
LM
Larson MG
HW
Harris WS
DS
Damrauer SM
SK
Stark KD
BS
Boekholdt SM
WN
Wareham NJ
PP
Pibarot P
AB
Arsenault BJ
MP
Mathieu P
GV
Gudnason V
OC
O'Donnell CJ
RJ
Rotter JI
TM
Tsai MY
PW
Post WS
CR
Clarke R
SS
Söderberg S
BY
Bossé Y
WQ
Wells QS
SJ
Smith JG
RD
Rader DJ
LM
Lathrop M
EJ
Engert JC
TG
Thanassoulis G
Chapter II

Abstract

Summary of the research findings

Importance: Aortic stenosis (AS) has no approved medical treatment. Identifying etiological pathways for AS could identify pharmacological targets.

3,469 European ancestry cases, 41,234 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

312118
Total Participants
GWAS
Study Type
Yes
Replicated
3,751 European ancestry cases, 236,142 European ancestry controls, 2,175 cases, 25,347 controls
Replication Participants
European
Ancestry
U.S., U.K., Sweden, Canada
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.