Effects of tumour necrosis factor on cardiovascular disease and cancer: A two-sample Mendelian randomization study.
Yuan S, Carter P, Bruzelius M et al.
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Tumour necrosis factor (TNF) inhibitors are used in the treatment of certain autoimmune diseases but given the role of TNF in tumour biology and atherosclerosis, such therapies may influence the risk of cancer and cardiovascular disease. We conducted a Mendelian randomization study to explore whether TNF levels are causally related to cardiovascular disease and cancer.
30,912 European ancestry individuals
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