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GWAS Study

Identifying novel genetic variants for brain amyloid deposition: a genome-wide association study in the Korean population.

Kim HR, Jung SH, Kim J et al.

34154648 PubMed ID
GWAS Study Type
1474 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

KH
Kim HR
JS
Jung SH
KJ
Kim J
JH
Jang H
KS
Kang SH
HS
Hwangbo S
KJ
Kim JP
KS
Kim SY
KB
Kim B
KS
Kim S
JJ
Jeong JH
YS
Yoon SJ
PK
Park KW
KE
Kim EJ
YB
Yoon B
JJ
Jang JW
HJ
Hong JY
CS
Choi SH
NY
Noh Y
KK
Kim KW
KS
Kim SE
LJ
Lee JS
JN
Jung NY
LJ
Lee J
KB
Kim BC
SS
Son SJ
HC
Hong CH
ND
Na DL
SS
Seo SW
WH
Won HH
KH
Kim HJ
Chapter II

Abstract

Summary of the research findings

Genome-wide association studies (GWAS) have identified a number of genetic variants for Alzheimer's disease (AD). However, most GWAS were conducted in individuals of European ancestry, and non-European populations are still underrepresented in genetic discovery efforts. Here, we performed GWAS to identify single nucleotide polymorphisms (SNPs) associated with amyloid β (Aβ) positivity using a large sample of Korean population.

629 Korean ancestry cases, 561 Korean ancestry controls

Chapter III

Study Statistics

Key metrics and study information

1474
Total Participants
GWAS
Study Type
Yes
Replicated
104 Korean ancestry cases, 180 Korean ancestry controls
Replication Participants
East Asian
Ancestry
Republic of Korea
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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