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GWAS Study

Genome-Wide Association Meta-Analysis Supports Genes Involved in Valve and Cardiac Development to Associate With Mitral Valve Prolapse.

Yu M, Kyryachenko S, Debette S et al.

34461747 PubMed ID
GWAS Study Type
8778 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

YM
Yu M
KS
Kyryachenko S
DS
Debette S
AP
Amouyel P
SJ
Schott JJ
LT
Le Tourneau T
DC
Dina C
NR
Norris RA
HA
Hagège AA
JX
Jeunemaitre X
BN
Bouatia-Naji N
Chapter II

Abstract

Summary of the research findings

Mitral valve prolapse (MVP) is a common cardiac valve disease, which affects 1 in 40 in the general population. Previous genome-wide association study has identified 6 risk loci for MVP. But these loci explained only partially the genetic risk for MVP. We aim to identify additional risk loci for MVP by adding data set from the UK Biobank.

1,920 European ancestry cases, 6,858 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

8778
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.K., France
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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