Polygenic Risk Scores for Kidney Function and Their Associations with Circulating Proteome, and Incident Kidney Diseases.
Yu Z, Jin J, Tin A et al.
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Abstract
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Genome-wide association studies (GWAS) have revealed numerous loci for kidney function (eGFR). The relationship between polygenic predictors of eGFR, risk of incident adverse kidney outcomes, and the plasma proteome is not known.
949,116 European ancestry individuals, 166,997 East Asian ancestry individuals, 21,338 South Asian ancestry individuals, 17,459 African American individuals, 4,961 Hispanic individuals
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