Effect of dietary calcium on the gender-specific association between polymorphisms in the PTPRD locus and osteoporosis.
Bae JH, Park D
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Background & aims: Osteoporosis is the most common bone disease and is characterized by low bone mineral density (BMD) and a high risk of fracture. Despite advances in our understanding of the pathogenesis of osteoporosis, complex gene-environment interactions that influence osteoporosis development remain largely unexplored. In this study, we aimed to identify genetic loci associated with low BMD and to evaluate these genetic variants under individual and environmental factors.
8,842 Korean ancestry individuals
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