Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset.
Saevarsdottir S, Stefansdottir L, Sulem P et al.
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Abstract
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Objectives: To find causal genes for rheumatoid arthritis (RA) and its seropositive (RF and/or ACPA positive) and seronegative subsets.
26,612 European ancestry cases, 869,454 European ancestry controls, 4,701 cases, 125,923 controls
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