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GWAS Study

Longitudinal lung function and gas transfer in individuals with idiopathic pulmonary fibrosis: a genome-wide association study.

Allen RJ, Oldham JM, Jenkins DA et al.

35985358 PubMed ID
GWAS Study Type
1329 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

AR
Allen RJ
OJ
Oldham JM
JD
Jenkins DA
LO
Leavy OC
GB
Guillen-Guio B
MC
Melbourne CA
MS
Ma SF
JJ
Jou J
KJ
Kim JS
FW
Fahy WA
OE
Oballa E
HR
Hubbard RB
NV
Navaratnam V
BR
Braybrooke R
SG
Saini G
RK
Roach KM
TM
Tobin MD
HN
Hirani N
WM
Whyte MKB
KN
Kaminski N
ZY
Zhang Y
MF
Martinez FJ
LA
Linderholm AL
AA
Adegunsoye A
SM
Strek ME
MT
Maher TM
MP
Molyneaux PL
FC
Flores C
NI
Noth I
GJ
Gisli Jenkins R
WL
Wain LV
Chapter II

Abstract

Summary of the research findings

Idiopathic pulmonary fibrosis (IPF) is an incurable lung disease characterised by progressive scarring leading to alveolar stiffness, reduced lung capacity, and impeded gas transfer. We aimed to identify genetic variants associated with declining lung capacity or declining gas transfer after diagnosis of IPF.

1,048 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

1329
Total Participants
GWAS
Study Type
Yes
Replicated
281 European ancestry individuals
Replication Participants
European
Ancestry
U.S., U.K., Spain
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.