A genome-wide association study identifies a novel association between SDC3 and apparent treatment-resistant hypertension.
Xiao X, Li R, Wu C et al.
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Abstract
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Compared with patients who require fewer antihypertensive agents, those with apparent treatment-resistant hypertension (aTRH) are at increased risk for cardiovascular and all-cause mortality, independent of blood pressure control. However, the etiopathogenesis of aTRH is still poorly elucidated.
556 Han Chinese ancestry cases, 802 Han Chinese ancestry controls
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