Genome-wide association study of treatment-related toxicity two years following radiotherapy for breast cancer.
Jandu HK, Veal CD, Fachal L et al.
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Abstract
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Background and purpose: Up to a quarter of breast cancer patients treated by surgery and radiotherapy experience clinically significant toxicity. If patients at high risk of adverse effects could be identified at diagnosis, their treatment could be tailored accordingly. This study was designed to identify common single nucleotide polymorphisms (SNPs) associated with toxicity two years following whole breast radiotherapy.
1,640 European ancestry individuals
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