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GWAS Study

Genetic Determinants of Multiple Sclerosis Susceptibility in People From Diverse Ancestral Backgrounds.

Jacobs BM, Schalk L, Tregaskis-Daniels E et al.

41791023 PubMed ID
GWAS Study Type
9456 Participants
81 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

JB
Jacobs BM
SL
Schalk L
TE
Tregaskis-Daniels E
SA
Scalfari A
NA
Nandoskar A
DA
Dunne A
GB
Gran B
MC
Mein CA
SC
Sellers C
SC
Spilker CE
RD
Rog DJ
VE
Visentin E
BE
Bezzina EL
UE
Uzochukwu E
TE
Tallantyre EC
WE
Wozniak E
SE
Sacre E
HG
Hassan-Smith G
FH
Ford HL
HJ
Harris J
BJ
Bradley J
BJ
Breedon J
BJ
Brooke J
KK
Kreft KL
GK
George K
PM
Papachatzaki MM
OM
O'Malley M
PM
Peter M
MM
Mattoscio M
AL
Azzopardi L
OR
Oliveira R
RN
Rhule N
EN
Evangelou N
VN
Vinod N
QO
Quinn O
AF
Ali F
SR
Shamji R
KR
Kaimal R
BR
Boulton R
TR
Tanveer R
TK
Tuite-Dalton K
MR
Middleton RM
MR
Murray R
BR
Bellfield R
HS
Hoque S
PS
Patel S
RS
Raj S
GS
Gumus S
MS
Mitchell S
SS
Sawcer SJ
AT
Arun T
PT
Pogreban T
BT
Brown TL
BT
Begum T
AV
Antoine V
RW
Rashid W
FG
Fawehinmi G
RC
Reidy C
BS
Begum S
BH
Bernard Healey SA
CH
Cummins H
WK
Westwood K
SD
Spencer D
FS
Farooq S
HK
Harding KE
WS
Williams S
RG
Radford G
WS
White S
AN
Alldred-Douglas N
FL
Fernandes L
HA
Harroud A
MJ
McCauley JL
BA
Beecham A
VN
Vince N
DS
Dos Santos Brito Silva N
MH
Morris HR
SE
Silber E
GG
Giovannoni G
NA
Noyce AJ
DR
Dobson R
Chapter II

Abstract

Summary of the research findings

Background and objectives: The genetic basis of multiple sclerosis (MS) susceptibility has been studied extensively in European (EUR) ancestry populations. The aim of our study was to determine the genetic architecture of MS susceptibility in people of South Asian (SAS) and African (AFR) genetic ancestral backgrounds.

254 South Asian ancestry cases, 9,202 South Asian ancestry controls

Chapter III

Study Statistics

Key metrics and study information

9456
Total Participants
GWAS
Study Type
No
Replicated
South Asian
Ancestry
U.K.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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