Menu
Currency
Skip to main content
HLA Heritage Report

See how your HLA region compares with world populations.

The HLA region on chromosome 6 is one of the most variable parts of the human genome. This report estimates which of 10 broad world regions that part of your DNA is most genetically similar to, and explains what the result does and does not mean.

One-time payment $44 Lifetime access. No subscription.
  • GDPR aligned
  • Private by default
  • Ancestry report, not a health test
What you get

Six things you will see in your report.

Each item below is a real section of the report, in the order you read it.

  1. Your top three regional signals

    The report opens with a headline summary: the three world regions your HLA region is most similar to, with their percentages, so you get the answer before the detail.

  2. Full percentage breakdown across 10 regions

    Every region with a signal is listed with its percentage, from largest to smallest. Select any region to open its detail panel.

  3. Global distribution map

    Your result drawn on a world map so you can see where the regions in your result sit. The shading is a visual guide, not a border or a claim about where your family lived.

  4. A profile for each region in your result

    Each region has a card with an image, your percentage, a plain statement of what that percentage means, and a longer description of the region and its reference populations.

  5. A plain-language science chapter

    What HLA is, the difference between HLA Class I and Class II genes, why chromosome 6 is so variable, and a clear list of the analysis limitations.

  6. Optional AI explanation Sold separately

    An AI assistant can explain your result in conversational language. It uses only the regions and percentages in your report, and its answers are informational, not proof of ancestry and not medical advice. It needs the separate AI Assistant licence.

Example result

What a result looks like.

A mock-up of the breakdown and region panel, so you know what to expect before you buy. The numbers are invented.

Illustrative example

HLA composition

10 regions

Invented percentages for illustration. This is not a customer result.

  1. 01Northwestern European38.0%
  2. 02Southern European24.5%
  3. 03West Asian12.0%
  4. 04Central & West Asian8.5%
  5. 05North African6.5%
  6. 06East African3.5%
  7. 07West African2.5%
  8. 08Southeast Asian2.0%
  9. 09East Asian1.5%
  10. 10Amerindian-Siberian1.0%

Top three regions, shown in the report summary.

Region panel, same example

Southern European 24.5%

The 24.5% shown here would indicate the proportion of the HLA region of your DNA that is most similar to reference populations from this region. It is a similarity estimate, not a statement about where your relatives lived.

Below this sentence the real panel adds an image of the region and a longer description of the region and its reference populations.

World map

The same regions drawn on a map, with a note that shading is a guide and not a border.

Science and limits

Class I and Class II genes explained, plus a list of what the analysis cannot do.

View sample report
The 10 regions

Broad world regions, not individual populations.

Your HLA region is compared against 10 continental-scale components. Each percentage in your report belongs to one of these.

Europe

  • Northwestern European
  • Southern European

Africa

  • North African
  • West African
  • East African

Asia

  • West Asian
  • Central & West Asian
  • East Asian
  • Southeast Asian

Americas and Siberia

  • Amerindian-Siberian
Why HLA

A different lens from a whole-genome estimate.

HLA genes help the immune system recognize what belongs in the body. They are among the most variable genes we have, and the region is inherited in long blocks. That makes it a useful, separate view of population similarity.

What it looks at
One region of chromosome 6 only. A whole-genome ancestry report averages across all chromosomes.
What it can add
A regional signal that can differ from, or add detail to, your other ancestry results.
Why results may differ
The HLA region has its own history and is shaped by different pressures than the rest of the genome. A difference is expected, not an error.
Best used as
A complement to a whole-genome report, not a replacement for one.
HLA Class I and Class II, in brief

Class I (HLA-A, -B, -C) is found on almost all cells and helps the immune system spot cells that are infected or abnormal.

Class II (HLA-DR, -DQ, -DP) is found on immune cells and helps start an immune response to things from outside the cell.

The report explains both in plain language. They are described for context only: the report does not report your HLA types and does not say anything about your health.

How it works

From your DNA file to your report.

  1. Use your DNA file

    Pick a sample already in your account, or upload a supported raw DNA file from a major testing company.

  2. We compare the HLA region

    Only the chromosome 6 HLA region of your data is compared with the reference model across the 10 regions.

  3. Open your report

    You get an email when it is ready. Your report stays in your account for lifetime access.

Get the Report

Compare your HLA region with world populations.

One chromosome 6 region, explained clearly, with its limits stated up front.

This report is included in the following packs:

Starter Pack $44 One-time payment - Lifetime access

A genetic-similarity estimate for one region of your genome, not a health test.

Secure payment · GDPR compliant · Your data stays yours

Before you begin

Frequently asked questions.

What HLA is, what the report shows, how to read it, and how your data is handled.

What is HLA?

HLA stands for Human Leukocyte Antigen. It is a group of genes on chromosome 6 that helps the immune system tell the body's own cells from foreign ones. It is one of the most variable regions of the human genome.

Is this a health or disease-risk report?

No. The report is an ancestry and population-genetics report. It does not predict disease, does not diagnose anything, and is not a substitute for clinical HLA typing or transplant matching.

What does the report actually show me?

It shows a percentage breakdown across 10 broad world regions, based on how similar the HLA region of your DNA is to reference populations in each region. It also includes a global map, a profile for each region in your result, and a plain-language science chapter.

Does it list my HLA types or alleles?

No. The report is a regional similarity breakdown. It is not a list of your HLA types.

Why does it only look at chromosome 6?

The HLA region sits on chromosome 6 and is shaped by different evolutionary pressures than most of the genome. Looking at it on its own gives a separate view that a whole-genome estimate does not provide.

Why might my HLA results differ from my other ancestry reports?

Whole-genome reports average across all chromosomes, while this report looks at one region that is inherited in long blocks and has its own history. Differences between the two are expected and do not mean either result is wrong.

How should I read small percentages?

Treat small values as tentative. They can reflect overlap between related reference populations, limited reference coverage, or statistical noise rather than a distinct connection.

What does a regional result mean?

A result measures statistical genetic similarity to reference populations in that region. It does not prove descent from a specific group, and it does not assign ethnicity, nationality or identity.

Which DNA files can I use?

DNA Genics accepts supported raw DNA files from major testing companies, including 23andMe, AncestryDNA, MyHeritage, FamilyTreeDNA and Living DNA, and supported whole genome sequencing formats.

How long does processing take?

Processing depends on your file and the current queue. You receive an email notification when your report is ready.

How is my data handled?

Your report is private by default, and your account provides controls for managing and deleting stored data.

What does lifetime access include?

The purchase gives you ongoing access to the report in your account without a subscription. Results may be recalculated if the underlying reference data or report method is updated.

Reading ancient and modern DNA since 2018

DNA Genics has been building ancestry and DNA analysis reports since 2018. Our reports come from years of work with our own reference panels, calculators and ancient-genome comparisons, developed and reviewed by our team. They are not generated on the fly or assembled as a side project. We use AI only in clearly labelled optional features.

About DNA Genics