Common genetic determinants of vitamin D insufficiency: a genome-wide association study.
Wang TJ, Zhang F, Richards JB et al.
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Abstract
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Vitamin D is crucial for maintenance of musculoskeletal health, and might also have a role in extraskeletal tissues. Determinants of circulating 25-hydroxyvitamin D concentrations include sun exposure and diet, but high heritability suggests that genetic factors could also play a part. We aimed to identify common genetic variants affecting vitamin D concentrations and risk of insufficiency.
16,125 European ancestry individuals
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