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GWAS Study

Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis.

Xie G, Roshandel D, Sherva R et al.

23740775 PubMed ID
GWAS Study Type
2570 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

XG
Xie G
RD
Roshandel D
SR
Sherva R
MP
Monach PA
LE
Lu EY
KT
Kung T
CK
Carrington K
ZS
Zhang SS
PS
Pulit SL
RS
Ripke S
CS
Carette S
DP
Dellaripa PF
EJ
Edberg JC
HG
Hoffman GS
KN
Khalidi N
LC
Langford CA
MA
Mahr AD
SC
St Clair EW
SP
Seo P
SU
Specks U
SR
Spiera RF
SJ
Stone JH
YS
Ytterberg SR
RS
Raychaudhuri S
DB
de Bakker PI
FL
Farrer LA
AC
Amos CI
MP
Merkel PA
SK
Siminovitch KA
Chapter II

Abstract

Summary of the research findings

Objective: To identify genetic determinants of granulomatosis with polyangiitis (Wegener's) (GPA).

459 European ancestry cases, 1,503 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

2570
Total Participants
GWAS
Study Type
Yes
Replicated
291 European ancestry cases, 317 European ancestry controls
Replication Participants
European
Ancestry
U.S., Canada
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

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