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GWAS Study

A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22.

Kerkhof HJ, Lories RJ, Meulenbelt I et al.

20112360 PubMed ID
GWAS Study Type
57530 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

KH
Kerkhof HJ
LR
Lories RJ
MI
Meulenbelt I
JI
Jonsdottir I
VA
Valdes AM
AP
Arp P
IT
Ingvarsson T
JM
Jhamai M
JH
Jonsson H
SL
Stolk L
TG
Thorleifsson G
ZG
Zhai G
ZF
Zhang F
ZY
Zhu Y
VD
van der Breggen R
CA
Carr A
DM
Doherty M
DS
Doherty S
FD
Felson DT
GA
Gonzalez A
HB
Halldorsson BV
HD
Hart DJ
HV
Hauksson VB
HA
Hofman A
IJ
Ioannidis JP
KM
Kloppenburg M
LN
Lane NE
LJ
Loughlin J
LF
Luyten FP
NM
Nevitt MC
PN
Parimi N
PH
Pols HA
RF
Rivadeneira F
SE
Slagboom EP
SU
Styrkársdóttir U
TA
Tsezou A
VD
van de Putte T
ZJ
Zmuda J
ST
Spector TD
SK
Stefansson K
UA
Uitterlinden AG
VM
van Meurs JB
Chapter II

Abstract

Summary of the research findings

Objective: To identify novel genes involved in osteoarthritis (OA), by means of a genome-wide association study.

1,341 European ancestry cases, 3,496 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

57530
Total Participants
GWAS
Study Type
Yes
Replicated
9,779 European ancestry cases, up to 31,818 European ancestry controls, 3,818 cases, 7,278 controls
Replication Participants
Other, European
Ancestry
U.S., Netherlands, Iceland, Greece, U.K.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.