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GWAS Study

Genome-wide association study to identify genetic determinants of severe asthma.

Wan YI, Shrine NR, Soler Artigas M et al.

22561531 PubMed ID
GWAS Study Type
5855 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

WY
Wan YI
SN
Shrine NR
SA
Soler Artigas M
WL
Wain LV
BJ
Blakey JD
MM
Moffatt MF
BA
Bush A
CK
Chung KF
CW
Cookson WO
SD
Strachan DP
HL
Heaney L
AB
Al-Momani BA
MA
Mansur AH
MS
Manney S
TN
Thomson NC
CR
Chaudhuri R
BC
Brightling CE
BM
Bafadhel M
SA
Singapuri A
NR
Niven R
SA
Simpson A
HJ
Holloway JW
HP
Howarth PH
HJ
Hui J
MA
Musk AW
JA
James AL
BM
Brown MA
BS
Baltic S
FM
Ferreira MA
TP
Thompson PJ
TM
Tobin MD
SI
Sayers I
HI
Hall IP
Chapter II

Abstract

Summary of the research findings

The genetic basis for developing asthma has been extensively studied. However, association studies to date have mostly focused on mild to moderate disease and genetic risk factors for severe asthma remain unclear.

933 European ancestry cases, 3,346 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

5855
Total Participants
GWAS
Study Type
Yes
Replicated
231 European ancestry cases, 1,345 European ancestry controls
Replication Participants
European
Ancestry
Australia, U.K.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

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