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GWAS Study

Novel genetic variants associated with inhaled corticosteroid treatment response in older adults with asthma.

Wang AL, Lahousse L, Dahlin A et al.

35501119 PubMed ID
GWAS Study Type
6851 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

WA
Wang AL
LL
Lahousse L
DA
Dahlin A
EA
Edris A
MM
McGeachie M
LS
Lutz SM
SJ
Sordillo JE
BG
Brusselle G
LJ
Lasky-Su J
WS
Weiss ST
IC
Iribarren C
LM
Lu MX
TK
Tantisira KG
WA
Wu AC
Chapter II

Abstract

Summary of the research findings

Introduction: Older adults have the greatest burden of asthma and poorest outcomes. The pharmacogenetics of inhaled corticosteroid (ICS) treatment response is not well studied in older adults.

3,097 European ancestry cases, 2,613 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

6851
Total Participants
GWAS
Study Type
Yes
Replicated
503 European ancestry cases, 638 European ancestry controls
Replication Participants
European
Ancestry
U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

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