Protective effect of club cell secretory protein (CC-16) on COPD risk and progression: a Mendelian randomisation study.
Milne S, Li X, Hernandez Cordero AI et al.
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Abstract
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The anti-inflammatory pneumoprotein club cell secretory protein-16 (CC-16) is associated with the clinical expression of chronic obstructive pulmonary disease (COPD). We aimed to determine if there is a causal effect of serum CC-16 level on the risk of having COPD and/or its progression using Mendelian randomisation (MR) analysis.
5,552 individuals
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