Biological function integrated prediction of severe radiographic progression in rheumatoid arthritis: a nested case control study.
Joo YB, Kim Y, Park Y et al.
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Radiographic progression is reported to be highly heritable in rheumatoid arthritis (RA). However, previous study using genetic loci showed an insufficient accuracy of prediction for radiographic progression. The aim of this study is to identify a biologically relevant prediction model of radiographic progression in patients with RA using a genome-wide association study (GWAS) combined with bioinformatics analysis.
120 Korean ancestry cases, 118 Korean ancestry controls
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