Genome-wide association study of microscopic colitis in the UK Biobank confirms immune-related pathogenesis.
Green HD, Beaumont RN, Thomas A et al.
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Background and aims: The causes of microscopic colitis are currently poorly understood. Previous reports have found clinical associations with coeliac disease and genetic associations at the human leukocyte antigen [HLA] locus on the ancestral 8.1 haplotype. We investigated pharmacological and genetic factors associated with microscopic colitis in the UK Biobank.
up to 98 European ancestry cases, up to 46,397 European ancestry controls
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