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GWAS Study

Evidence for causal effects of lifetime smoking on risk for depression and schizophrenia: a Mendelian randomisation study.

Wootton RE, Richmond RC, Stuijfzand BG et al.

31689377 PubMed ID
GWAS Study Type
462690 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

WR
Wootton RE
RR
Richmond RC
SB
Stuijfzand BG
LR
Lawn RB
SH
Sallis HM
TG
Taylor GMJ
HG
Hemani G
JH
Jones HJ
ZS
Zammit S
DS
Davey Smith G
MM
Munafò MR
Chapter II

Abstract

Summary of the research findings

Smoking prevalence is higher amongst individuals with schizophrenia and depression compared with the general population. Mendelian randomisation (MR) can examine whether this association is causal using genetic variants identified in genome-wide association studies (GWAS).

462,690 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

462690
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.K.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

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