Investigating the shared genetic architecture of post-traumatic stress disorder and gastrointestinal tract disorders: a genome-wide cross-trait analysis.
Zhou S, Luo H, Tian Y et al.
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Abstract
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Observational studies suggest a correlation between post-traumatic stress disorder (PTSD) and gastrointestinal tract (GIT) disorders. However, the genetic overlap, causal relationships, and underlining mechanisms between PTSD and GIT disorders were absent.
at least 23,212 European ancestry cases, at least 151,447 European ancestry controls (MTAG boosted by gastrointestinal tract disorder samples)
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