Sepsis-associated acute respiratory distress syndrome in individuals of European ancestry: a genome-wide association study.
Guillen-Guio B, Lorenzo-Salazar JM, Ma SF et al.
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Abstract
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Acute respiratory distress syndrome (ARDS) is a lung inflammatory process caused mainly by sepsis. Most previous studies that identified genetic risks for ARDS focused on candidates with biological relevance. We aimed to identify novel genetic variants associated with ARDS susceptibility and to provide complementary functional evidence of their effect in gene regulation.
274 European ancestry cases, 316 European ancestry controls
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