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GWAS Study

Genome-wide meta-analysis identifies nine loci associated with higher risk of hepatocellular carcinoma development.

Ghouse J, Gellert-Kristensen H, O'Rourke CJ et al.

40823170 PubMed ID
GWAS Study Type
2103299 Participants
195 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

GJ
Ghouse J
GH
Gellert-Kristensen H
OC
O'Rourke CJ
SA
Seidelin AS
TG
Thorleifsson G
SG
Sveinbjörnsson G
TV
Tragante V
KC
Konkwo C
BJ
Brancale J
VS
Vilarinho S
ET
Eyrich TM
AG
Ahlberg G
BJ
Bundgaard JS
RS
Rand SA
LP
Lundegaard PR
SE
Sørensen E
MC
Mikkelsen C
TJ
Træholt J
EC
Erikstrup C
DK
Dinh KM
BM
Bruun MT
JB
Jensen BA
BJ
Bay JT
BS
Brunak S
BK
Banasik K
UH
Ullum H
LT
Laisk T
MR
Mägi R
NL
Nadauld LD
KK
Knowlton KU
KS
Knight S
GL
Gluud LL
VK
Vistisen K
BE
Björnsson ES
UM
Ulfarsson MO
SP
Sulem P
HH
Holm H
PO
Pedersen OB
OS
Ostrowski SR
GD
Gudbjartsson DF
RT
Rafnar T
SK
Stefansson K
LU
Lassen U
PH
Pommergaard HC
HJ
Hillingsø JG
AJ
Andersen JB
BH
Bundgaard H
SS
Stender S
Chapter II

Abstract

Summary of the research findings

Background & aims: The genetic underpinnings of hepatocellular carcinoma (HCC) remain largely unknown. Thus, we aimed to identify new genetic risk loci for HCC.

2,792 East Asian ancestry cases, 235,223 East Asian ancestry controls, 3,748 European ancestry cases, 1,861,536 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

2103299
Total Participants
GWAS
Study Type
No
Replicated
East Asian, European
Ancestry
Japan, China, U.S., Belgium, Finland, Denmark, U.K., France, Iceland, Germany, Estonia
Recruitment Country
Chapter IV

AI-Generated Summary

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