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Genetic dissection of stool frequency implicates vitamin B1 metabolism and other actionable pathways in the modulation of gut motility.

Díaz-Muñoz C, Bozzarelli I, Lopera-Maya EA et al.

41558814 PubMed ID
GWAS Study Type
167966 Participants
157 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

DC
Díaz-Muñoz C
BI
Bozzarelli I
LE
Lopera-Maya EA
BL
Belbasis L
LF
Lo Faro V
CT
Camargo Tavares L
HF
Heredia-Fernández F
DL
Di Lorenzo B
ST
Sinha T
EB
Esteban Blanco C
FM
Favé MJ
AP
Awadalla P
WR
Walters RG
BF
Bonfiglio F
ZA
Zhernakova A
SS
Sanna S
DM
D'Amato M
Chapter II

Abstract

Summary of the research findings

Genetic studies of stool frequency (SF), an indirect proxy for gastrointestinal transit, may reveal therapeutically tractable pathways relevant to IBS and other dysmotility disorders.

167,966 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

167966
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Canada, Netherlands, Belgium, U.K.
Recruitment Country
Chapter IV

AI-Generated Summary

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