Association of a common nonsynonymous variant in GLUT9 with serum uric acid levels in old order amish.
McArdle PF, Parsa A, Chang YP et al.
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Abstract
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Objective: Uric acid is the primary end product of purine metabolism. Increased serum uric acid levels have been associated with gouty arthritis as well as with a variety of cardiovascular-related phenotypes. This study was undertaken to investigate associations between uric acid levels and single-nucleotide polymorphisms (SNPs).
408 Old Order Amish female individuals, 460 Old Order Amish male individuals
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