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GWAS Study

Genome-wide association study identifies HLA-DR variants conferring risk of HBV-related acute-on-chronic liver failure.

Tan W, Xia J, Dan Y et al.

28130311 PubMed ID
GWAS Study Type
3367 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

TW
Tan W
XJ
Xia J
DY
Dan Y
LM
Li M
LS
Lin S
PX
Pan X
WH
Wang H
TY
Tang Y
LN
Liu N
TS
Tan S
LM
Liu M
HW
He W
ZW
Zhang W
MQ
Mao Q
WY
Wang Y
DG
Deng G
Chapter II

Abstract

Summary of the research findings

Objective: Acute-on-chronic liver failure (ACLF) is an extreme condition after severe acute exacerbation of chronic hepatitis B; however, the underlying genetic factors involved in its onset and progression are currently unclear.

389 Chinese ancestry cases, 391 Chinese ancestry controls

Chapter III

Study Statistics

Key metrics and study information

3367
Total Participants
GWAS
Study Type
Yes
Replicated
901 Chinese ancestry cases, 1,686 Chinese ancestry controls
Replication Participants
East Asian
Ancestry
China
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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